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conventional and atypical antipsychotics |
| Antipsychotics |
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NEW WARNING
The Food and Drug Administration has issued an alert for health care professionals regarding the use of conventional antipsychotics (prochlorperazine, haloperidol, loxapine, thioridazine, molindone, thiothixene, pimozide, fluphenazine, trifluoperazine, chlorpromazine, perphenazine) and atypical antipsychotics (aripiprazole, clozapine, ziprasidone, paliperidone, risperidone, quetiapine, olanzapine, olanzapine-fluoxetine). All manufacturers of these drugs are required to add a boxed warning and warning to the drugs' prescribing information about the increased risk of death in elderly patients with dementia-related psychosis. Antipsychotics aren't approved for treatment of dementia-related psychosis. Health care professionals who prescribe antipsychotics to an elderly patient with dementia-related psychosis should discuss the risk of increased mortality with the patient, his family, and his caregivers.
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